The patient postoperative pain scores (VAS score) gradually decreased. The imaging stabilities of the hip joints 3 and 12 months after operation were significantly higher than those before operation (P<0.05). The excellent rates 3 and 12 months after operation were significantly higher than those before operation (P<0.05). The patients hip functions were assessed on the basis of the Harris hip score, 3 and 12 months after operation. The mean operation time was 34.6☑4.2 min, and the intraoperative blood loss was 23.6☘.9 mL. Results: all of the 76 patients were successfully operated and included in the study. The preoperative and postoperative pain scores measured by visual analogy score (VAS) were also recorded and compared. The operation time, intraoperative blood loss, and perioperative complications were also recorded intraoperatively to evaluate the clinical efficacy and safety. After treatment, the patients were followed-up for 12 months. All the patients were treated by core decompression with synthetic calcium-sulfate bone grafting. Method: a total of 76 patients with non-traumatic osteonecrosis of the femoral head were admitted to our hospital from February 2012 to November 2014 and included in the study. * Corresponding author: Jing Hao to investigate the safety and long-term efficacy of core decompression with synthetic calcium-sulfate bone grafting on non-traumatic osteonecrosis of the femoral head. Department of trauma orthopedics, 6th affiliated hospital of Wenzhou medical university (Lishui People’s Hospital), Lishui Zhejiang province, 323000 PR Chinaĭepartment of general surgery, 6th affiliated hospital of Wenzhou medical university (Lishui People’s Hospital), Lishui Zhejiang province, No.15 Dazhong Road, Liandu district, Lishui 323000 PR China
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